In the United States, if poisoning is suspected, Poison Control (available 24/7 at 1-80) should be contacted immediately to obtain information from specialists regarding management. The focus of this article is poisoning from organophosphates, cyanide, ethylene glycol and methanol, laundry and cleaning products, mushrooms and plants, and carbon dioxide. Substances that are commonly thought to be harmless, such as water and most vitamins, can also be harmful if taken in excess. The type of poison, the amount taken, and the size and age of the individual involved are all factors that determine if a substance is actually harmful.
Death, if it occurs, is usually within 1-6 days.Poisoning occurs when a substance that is inhaled, ingested, or absorbed through the skin has harmful effects or even causes death. Morbidity/recovery related to site of hemorrhage. 
Clinical signs of poisoning usually appear 3-5 days following ingestion. Toxicity may be potentiated by phenylbutazone, diphenylhydantoin, adrenocorticosteroids, and sulfonamides. Signs do not develop until body reserves of vitamin K have been depleted, ie >24 hours after ingestion of rodenticide. Second generation (longer acting) rodenticides (eg diphacinone, brodifacoum and bromadiolone) may produce a coagulopathy after a single dose and toxic effects may persist for more than 3 weeks. Short acting rodenticides (eg warfarin, coumafuryl and pindone) generally require multiple exposures before coagulopathy occurs and toxic effects may resolve after 7 to 10 days. Depletion of clotting factors results in coagulopathy and profuse bleeding following trauma. Factor VII has shortest half-life and is therefore first to be affected by anti-coagulant poisoning. Clotting factors II (prothrombin), VII, IX and X all require active vitamin K to function effectively. Anticoagulant rodenticides inhibit Vitamin K epoxide reductase, the enzyme involved in production of active vitamin K. Reported acute oral LD 50s for the cat:. Cats are less often poisoned by dogs, but poisoning may follow ingestion of poisoned rodents.
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